Cardiff welcome six internationals back into their starting line-up as Harlequins visit the Arms Park for Friday’s Heineken Champions Cup clash (KO 8.00pm).
A number of senior stars will make their first European appearance of the season, having missed the opening two rounds of action following well-documented travel restrictions in South Africa.
After missing out on last week’s trip to Edinburgh, British and Irish Lion Josh Adams is introduced back onto the wing, joining Owen Lane and the returning Hallam Amos in an all-international back three.
Willis Halaholo and Rey Lee-Lo continue their partnership in midfield while a new-look half back duo of Jarrod Evans and Tomos Williams is welcomed back, having featured from the bench in the Scottish capital.
Hooker Kirby Myhill is passed fit to take his place in an unchanged front row, but skipper Josh Turnbull switches to the second row to combine with Seb Davies in the boiler room.
The side is completed as Shane Lewis-Hughes, Ellis Jenkins and James Ratti are given the nod in the back row.
Looking ahead to the crucial pool stage encounter, director of rugby Dai Young said: “We can be really proud of the way the group came together to perform admirably in the opening two rounds in Europe back in December.
“The senior guys did a great job to lead the more inexperienced players during that period and they’ve taken confidence from that. I’d like to think it brought us a bit closer together. It was a difficult period but we stuck together and hopefully we’ve come out as a closer unit.
“For all the positives however, they were two defeats and we want to win every game we are involved in. We are determined to go one better this time around but know the quality that we face.
“With the way the competition is set out this year, we know that every point will be crucial and we’re really excited for the challenge on Friday against a good Quins outfit.
“We were disappointed last week up in Edinburgh, but there’s been no time to feel sorry for ourselves. Training has been sharp in the build and we’re looking forward for the opportunity to bounce back as we return to play at the Arms Park."
Wales prop Dillon Lewis recovers from a foot injury to take his place on the bench, with Ben Thomas in line for his first Blue and Blacks outing since October.
With Liam Belcher, Iestyn Harris, Efan Daniel and Kristian Dacey all sidelined with injuries, Carmarthen Quins hooker Torin Myhill, brother of Kirby, is drafted in to cover from the bench.
Cardiff Rugby: Hallam Amos; Owen Lane, Rey Lee-Lo, Uilisi Halaholo, Josh Adams; Jarrod Evans, Tomos Williams; Rhys Carré, Kirby Myhill, Dmitri Arhip, Josh Turnbull (capt.), Seb Davies, Shane Lewis-Hughes, Ellis Jenkins, James Ratti
Replacements: Torin Myhill, Corey Domachowski, Dillon Lewis, Rory Thornton, Will Boyde, Lloyd Williams, Rhys Priestland, Ben Thomas