Blaine Scully will captain USA as they welcome Scotland to Houston, Texas on Saturday.
Following last week's 62-13 victory over Russia, Gary Gold has kept faith with his starting XV, making only two changes to the bench.
Scully lines up alongside former Cardiff Blues team-mate, Cam Dolan, who wears the number eight jersey.
The encounter sees the Sacramento-born wing pick up his 38th international cap. The Eagles will conclude their summer Tests as they take on rivals Canada in Nova Scotia next week.
USA: 15 Will Hooley, 14 Blaine Scully (c), 13 Bryce Campbell, 12 Paul Lasike, 11 Marcel Brache, 10 AJ MacGinty, 9 Shaun Davies, 8 Cam Dolan, 7 Hanco Germishuys, 6 John Quill, 5 Nick Civetta, 4 Samu Manoa, 3 Paul Mullen, 2 Joe Taufete’e, 1 Eric Fry
Replacements: 16 Dylan Fawsitt, 17 Titi Lamositele, 18 Chris Baumann, 19 Greg Peterson, 20 Ben Landry, 21 Nate Augspurger, 22 Will Magie, 23 Dylan Audsley